abstract：:Identification of lipophilic chemicals requires the development of new techniques to detect these compounds at the cellular and subcellular levels. To address this issue, we have developed a combinational protocol using antibodies directed against chemicals together with a multiple signal amplification system (catalyz...

journal_title：Environmental toxicology and chemistry

authors： Einsporn S,Koehler A

更新日期：2008-03-01 00:00:00

abstract：:Lake whitefish (Coregonus clupeaformis) were fed rainbow smelt (Osmerus mordax) in four laboratory tanks over a 133-d experiment. At the start of the experiment, 10 to 14 of the fish in each tank were sacrificed, and the concentrations of 40 polychlorinated biphenyl (PCB) congeners within these fish were determined. P...

journal_title：Environmental toxicology and chemistry

authors： Madenjian CP,O'Connor DV,Rediske RR,O'Keefe JP,Pothoven SA

更新日期：2008-03-01 00:00:00

abstract：:Heavy metals can cause a decrease in the taxonomic diversity of soil communities. Because of functional redundancy, it remains unclear to what extent different functions performed by the soil microbial communities may be affected by pollution. We studied the impact of metal contamination on soil bacterial and fungal f...

journal_title：Environmental toxicology and chemistry

authors： Stefanowicz AM,Niklińska M,Laskowski R

更新日期：2008-03-01 00:00:00

abstract：:A method is proposed for estimating metabolic biotransformation rate constants for nonionic organic chemicals from measured laboratory bioconcentration and dietary bioaccumulation data in fish. Data have been selected based on a quality review to reduce uncertainty in the measured values. A kinetic mass balance model ...

journal_title：Environmental toxicology and chemistry

authors： Arnot JA,Mackay D,Bonnell M

更新日期：2008-02-01 00:00:00

abstract：:The continental population of scaup has declined over the last three decades to levels that remain well below conservation goals. One proposed hypothesis for this decline is that increasing exposure to contaminants has led to decreased fitness in scaup, and selenium (Se) has been identified as a contaminant of concern...

journal_title：Environmental toxicology and chemistry

authors： DeVink JM,Clark RG,Slattery SM,Scheuhammer TM

更新日期：2008-02-01 00:00:00

abstract：:A comprehensive gas chromatographic-high-resolution mass spectrometric (GC-HRMS)-based method was developed that permitted the simultaneous determination of 30 estrogenic endocrine-disrupting chemicals (EDCs) and related compounds, including surfactants, biogenic and synthetic steroids, fecal sterols, phytoestrogens, ...

journal_title：Environmental toxicology and chemistry

authors： Ikonomou MG,Cai SS,Fernandez MP,Blair JD,Fischer M

更新日期：2008-02-01 00:00:00

abstract：:During laboratory and field studies, a fraction of contaminants in soils or sediments often is observed to be highly resistant to desorption. This desorption-resistant fraction may have significant effects on long-term fate and exposure of soil/ sediment-bound contaminants in particular, causing much reduced availabil...

journal_title：Environmental toxicology and chemistry

authors： Chen W,Cong L,Hu H,Zhang P,Li J,Feng Z,Kan AT,Tomson MB

更新日期：2008-01-01 00:00:00

abstract：:Polycyclic musks were measured in surface sediments collected from the Pearl River Delta and Macao coastal region, South China, to investigate contamination from domestic sewage. Three polycyclic musk compounds-4-acetyl-1,1-dimethyl-6-tert-butylindan, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta(g)-2-benzopy...

journal_title：Environmental toxicology and chemistry

authors： Zeng X,Mai B,Sheng G,Luo X,Shao W,An T,Fu J

更新日期：2008-01-01 00:00:00

abstract：:The mab-3 of Caenorhabditis elegans and doublesex of Drosophila are two sex-determining genes that are found to have only a common DNA binding motif called a doublesex and mab-3 (DM) domain among phyla. The DM domain regulates some aspects of sexual development such as yolk protein synthesis. In the present study, by ...

journal_title：Environmental toxicology and chemistry

authors： Zhang X,Zha J,Wang Z

更新日期：2008-01-01 00:00:00

abstract：:A feasible method has been optimized to simultaneously determine multiclass antibiotic residues, including sulfonamides, fluoroquinolones, trimethoprim, and chloramphenicol in urban riverine water and wastewater by off-line solid phase extraction and high-performance liquid chromatography coupled with a diode-array ul...

journal_title：Environmental toxicology and chemistry

authors： Peng X,Tan J,Tang C,Yu Y,Wang Z

更新日期：2008-01-01 00:00:00

abstract：:The present study investigates the germination and growth of Triticum aestivum exposed to two different microcystins (microcystin-LR [where the two variable places in the toxin molecule are leucine (L) and arginine (R) (MC-LR)] and microcystin-RR) and to cell-free cyanobacterial crude extract containing MC-LR. The con...

journal_title：Environmental toxicology and chemistry

authors： Pflugmacher S,Hofmann J,Hübner B

更新日期：2007-12-01 00:00:00

abstract：:We analyzed the fate of organotins in seawater and sediments from Tokyo Bay, Japan, by gas chromatography/inductively coupled plasma mass spectrometry. We also measured the toxicity of methylated butyltins by in vitro bioassays, the retinoid X receptor (RXR) activation method, and the marine luminescent bacterium Vibr...

journal_title：Environmental toxicology and chemistry

authors： Kurihara R,Shiraishi F,Rajendran RB,Tao H,Horiguchi F,Nakata K,Hashimoto S

更新日期：2007-12-01 00:00:00

abstract：:In some kinetic studies with aquatic invertebrates, the bioaccumulation of polyaromatic hydrocarbons (PAHs) has been observed to peak at the beginning of the test. This has been explained by the depletion of PAHs from pore water due to limited desorption during the bioaccumulation test or, alternatively, by the activa...

journal_title：Environmental toxicology and chemistry

authors： Lyytikäinen M,Pehkonen S,Akkanen J,Leppänen M,Kukkonen JV

更新日期：2007-12-01 00:00:00

abstract：:In plant tissues, xenobiotics often are conjugated with natural constituents such as sugars, amino acids, glutathione, and malonic acid. Usually, conjugation processes result in a decrease in the reactivity and toxicity of xenobiotics by increasing the water solubility and polarity of conjugates, and reducing their mo...

journal_title：Environmental toxicology and chemistry

authors： Laurent F,Canlet C,Debrauwer L,Pascal-Lorber S

更新日期：2007-11-01 00:00:00

abstract：:Development of a terrestrial biotic ligand model (TBLM) for higher plants requires a root-Cu accumulation value that corresponds to the 50% inhibitory concentration (IC50). However, it is not yet known which of the two previously reported Cu-binding ligands on the root is associated with Cu toxicity. The aim of the pr...

journal_title：Environmental toxicology and chemistry

authors： Antunes PM,Hale BA,Ryan AC

更新日期：2007-11-01 00:00:00

abstract：:The fate and effects of cytostatic (anticancer or antineoplastic) pharmaceuticals in the environment are largely unknown, but they can contaminate wastewater treatment effluents and consequently aquatic ecosystems. In this paper, we have focused on five cytostatic compounds used in high amounts (cyclophosphamide, cisp...

journal_title：Environmental toxicology and chemistry

authors： Zounková R,Odráska P,Dolezalová L,Hilscherová K,Marsálek B,Bláha L

更新日期：2007-10-01 00:00:00

abstract：:Few studies have investigated the potential reproductive effects of toxicants on Australian freshwater fish species. The present study uses the Australian rainbowfish (Melanotaenia fluviatilis) as a model for testing the potential effects of 17beta-estradiol. Groups of reproductively active rainbowfish were exposed to...

journal_title：Environmental toxicology and chemistry

authors： Pollino CA,Georgiades E,Holdway DA

更新日期：2007-10-01 00:00:00

abstract：:Native freshwater mussels (family Unionidae) are among the most imperiled faunal groups in the world. Factors contributing to the decline of mussel populations likely include pesticides and other aquatic contaminants; however, there is a paucity of data regarding the toxicity of even the most globally distributed pest...

journal_title：Environmental toxicology and chemistry

authors： Bringolf RB,Cope WG,Mosher S,Barnhart MC,Shea D

更新日期：2007-10-01 00:00:00

abstract：:3-Methyl-4-nitrophenol (PNMC) is a component of diesel exhaust particles and one of the major breakdown products of the insecticide fenitrothion. This chemical has a high potential for reproductive toxicity in Japanese quail (Coturnix japonica) and rats. Because PNMC inhaled by the body is metabolized by uridine dipho...

journal_title：Environmental toxicology and chemistry

authors： Lee CH,Kamijima M,Li C,Taneda S,Suzuki AK,Nakajima T

更新日期：2007-09-01 00:00:00

abstract：:The toxicity and uptake of polycyclic aromatic hydrocarbons (PAHs) by earthworms were measured in soil samples collected from manufactured-gas plant sites having a wide range in PAH concentrations (170-42,000 mg/kg) and soil characteristics. Samples varied from vegetated soils to pure lampblack soot and had total orga...

journal_title：Environmental toxicology and chemistry

authors： Kreitinger JP,Quiñones-Rivera A,Neuhauser EF,Alexander M,Hawthorne SB

更新日期：2007-09-01 00:00:00

abstract：:Atrazine is a well-known contaminant of surface waters and has been implicated in point-source pollution at agrochemical dealerships in the Midwest. Although the fate of atrazine has been well documented in soil and water, little is known about the fate of this contaminant and its metabolites within a grassed system. ...

journal_title：Environmental toxicology and chemistry

authors： Henderson KL,Belden JB,Coats JR

更新日期：2007-09-01 00:00:00

abstract：:Induction of the cytochrome P4501A (CYP1A) enzyme system in fish is a common biomarker of exposure to aromatic hydrocarbons. Induction of CYP1A can be measured at a number of steps in the transcription-translation-functional protein pathway using a variety of techniques. The present study examined the range of these m...

journal_title：Environmental toxicology and chemistry

authors： Oris JT,Roberts AP

更新日期：2007-08-01 00:00:00

abstract：:Toxicity of cadmium to early life stages of brown trout (Salmo trutta) was determined at multiple water hardnesses. Increasing water hardness decreased cadmium toxicity. Postswimup fry were much more sensitive than embryos and larvae. Chronic values from early life stage tests initiated with eyed embryos were 3.52, 6....

journal_title：Environmental toxicology and chemistry

authors： Brinkman SF,Hansen DL

更新日期：2007-08-01 00:00:00

abstract：:Retinoids are known to regulate important processes such as differentiation, development, and embryogenesis. Some effects, such as malformations in frogs or changes in metabolism of birds, could be related to disruption of the retinoid signaling pathway by exposure to organic contaminants. A new reporter gene assay ha...

journal_title：Environmental toxicology and chemistry

authors： Novák J,Benísek M,Pacherník J,Janosek J,Sídlová T,Kiviranta H,Verta M,Giesy JP,Bláha L,Hilscherová K

更新日期：2007-08-01 00:00:00

abstract：:Military activities associated with training have resulted in soil residues of munition compounds and their breakdown products. Often, these areas are valuable habitats used by birds. To evaluate the possibility of adverse effects in birds, the effects from oral exposures of 2,6-dinitrotoluene (2,6-DNT) and 1,3,5-trin...

journal_title：Environmental toxicology and chemistry

authors： Johnson MS,Quinn MJ,Bazar MA,Gust KA,Escalon BL,Perkins EJ

更新日期：2007-07-01 00:00:00

abstract：:We coupled intensive population monitoring with collection of blood samples from 383 nesting Pacific common eiders (Somateria mollisima v-nigrum) at two locations in Alaska (USA) from 2002 to 2004. We investigated annual, geographic, and within-season variation in blood concentrations of lead and selenium; compared ex...

journal_title：Environmental toxicology and chemistry

authors： Wilson HM,Flint PL,Powell AN

更新日期：2007-07-01 00:00:00

abstract：:Rapid expression of heat shock protein (hsp) families in response to a variety of stressors has been demonstrated in many organisms, including fish. The present 60-d challenge study was designed to compare hsp induction in juvenile Chinook salmon following exposure to individual pesticides, virus, and both stressors c...

journal_title：Environmental toxicology and chemistry

authors： Eder KJ,Köhler HR,Werner I

更新日期：2007-06-01 00:00:00

abstract：:This study evaluated the toxic effects of substituted anilines on Pseudokirchneriella subcapitata with the use of a closed algal toxicity testing technique with no headspace. Two response endpoints (i.e., dissolved oxygen production [DO] and algal growth rate) were used to evaluate the toxicity of anilines. Both DO an...

journal_title：Environmental toxicology and chemistry

authors： Chen CY,Ko CW,Lee PI

更新日期：2007-06-01 00:00:00

abstract：:Genetic diversity among laboratory and field populations of Chironomus riparius was investigated using microsatellite DNA analysis. Individuals of midge cultures reared in 10 different laboratories showed a clear reduction in the number of alleles per locus and in the level of heterozygosity compared to two natural po...

journal_title：Environmental toxicology and chemistry

authors： Nowak C,Vogt C,Diogo JB,Schwenk K

更新日期：2007-05-01 00:00:00

abstract：:Synthetic sea salts are often used to adjust the salinity of effluent, ambient, and laboratory water samples to perform toxicity tests with marine and estuarine species. The U.S. Environmental Protection Agency (U.S. EPA) provides guidance on salinity adjustment in its saltwater test guidelines. The U.S. EPA suggests ...

journal_title：Environmental toxicology and chemistry

authors： Arnold WR,Cotsifas JS,Winter AR,Klinck JS,Smith DS,Playle RC

更新日期：2007-05-01 00:00:00

abstract：:Eight propylene glycol substances, ranging from 1,2-propanediol to a poly(propylene glycol) (PPG) having number-average molecular weight (M(n)) of 2,700 (i.e., PPG 2700), were evaluated in the Organization for Economic Cooperation and Development (OECD) ready- and seawater biodegradability tests. Uniformity in test pa...

journal_title：Environmental toxicology and chemistry

authors： West RJ,Davis JW,Pottenger LH,Banton MI,Graham C

更新日期：2007-05-01 00:00:00

abstract：:Hydroponic cultures were conducted to investigate the effects of the biodegradable chelating agent S,S-ethylenediaminedisuccinic acid (EDDS) on the growth and copper uptake by garland chrysanthemum (Chrysanthemum coronarium L.), a plant species sensitive to soil chelate amendment. In the presence of 50 micromol/L Cu, ...

journal_title：Environmental toxicology and chemistry

authors： Wei L,Luo C,Wang C,Li X,Shen Z

更新日期：2007-04-01 00:00:00

abstract：:Stenotrophomonas sp. CD02 was isolated from a site that previously had been contaminated with high concentrations of the heavy metals cadmium (3 mg kg(-1)) and chromium (115 mg kg(-1)). This strain was able to grow on complex (Luria Bertani) medium containing high concentrations of cadmium ion (up to 4 mM). Additional...

journal_title：Environmental toxicology and chemistry

authors： Chien CC,Hung CW,Han CT

更新日期：2007-04-01 00:00:00

abstract：:Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that has been detected widely in surface waters in North America and Europe. The impact of diclofenac on river biofilm communities was investigated at exposures of 10 and 100 microg L(-1) of diclofenac or its molar equivalent in carbon and nutrients. Experime...

journal_title：Environmental toxicology and chemistry

authors： Lawrence JR,Swerhone GD,Topp E,Korber DR,Neu TR,Wassenaar LI

更新日期：2007-04-01 00:00:00

abstract：:Prediction of pulsed or intermittent exposure effects on populations is emerging as an important issue in ecotoxicology. However, the underlying theory of the dose-response models has not been tested rigorously enough to provide a true understanding for predicting the effects of pulsed exposures. Since its introductio...

journal_title：Environmental toxicology and chemistry

authors： Zhao Y,Newman MC

更新日期：2007-03-01 00:00:00

abstract：:Uptake of cadmium from water by freshwater animals has been well documented. However, little attention has been given to the importance of dietary and combined exposure as the source for uptake. In the present study, we compared cadmium uptake from waterborne (water-only), dietary (food-only), and combined (water plus...

journal_title：Environmental toxicology and chemistry

authors： Sofyan A,Rosita G,Price DJ,Birge WJ

更新日期：2007-03-01 00:00:00

abstract：:Strong positive correlations between selenium (Se) and total mercury (HgT) contents in the liver of marine mammals and mercury mine workers in modern times have been documented in numerous investigations. Herein, we report a positive correlation between Se and HgT concentrations over the past 1,500 years in the seal h...

journal_title：Environmental toxicology and chemistry

authors： Yin X,Sun L,Zhu R,Liu X,Ruan D,Wang Y

更新日期：2007-03-01 00:00:00

abstract：:This study examined the bioaccumulation and dietary retention of 61 polychlorinated biphenyl (PCB) and four polybrominated diphenyl ether (PBDE) congeners in juvenile American kestrels (Falco sparverius). American kestrels were exposed to contaminants via egg injection and daily gavage dosing over the posthatch-to-fle...

journal_title：Environmental toxicology and chemistry

authors： Drouillard KG,Fernie KJ,Letcher RJ,Shutt LJ,Whitehead M,Gebink W,Bird DM

更新日期：2007-02-01 00:00:00

abstract：:Although many studies have reported that nitroaromatics such as 2,4,6-trinitrotoluene (TNT) have strong mutagenicity, the mechanism of mutagenic activity in these compounds has not yet been reported. We examined the mutagenicity versus reactivity and biodegradation by bacteria using TNT and its analogs (1,3,5-trinitro...

journal_title：Environmental toxicology and chemistry

authors： Maeda T,Nakamura R,Kadokami K,Ogawa HI

更新日期：2007-02-01 00:00:00

abstract：:Some toxicology research in which toxicant exposures are continual (pulsed) rather than continuous have been reported. A number of toxicity models have been developed for pulsed and continuous exposures. Most of these models were developed based on one- or two-compartment, first-order toxicokinetics and were calibrate...

journal_title：Environmental toxicology and chemistry

authors： Hoang TC,Tomasso JR,Klaine SJ

更新日期：2007-01-01 00:00:00